With nothing left to lose, Barry takes on Savitar in an epic conclusion to season three.
- Grant Gustin as Barry Allen/The Flash and Barry Allen/Savitar
- Candice Patton as Iris West
- Danielle Panabaker as Caitlin Snow/Killer Frost
- Carlos Valdes as Cisco Ramon/Vibe
- Keiynan Lonsdale as Wally West/Kid Flash
- Tom Cavanagh as Harrison "H.R." Wells and Harrison "Harry" Wells
- Jesse L. Martin as Joe West
- Tom Felton as Julian Albert (special appearance)
- Jessica Camacho as Gypsy
- Anne Dudek as Tracy Brand
- Michelle Harrison as Nora Allen
- John Wesley Shipp as Jay Garrick/The Flash
- Andre Tricoteux as Savitar (voice)
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