It arrives on DVD and Blu-ray on November 9, 2021.
"Having spent last season trying to track down the Loom of Fate in order to bring back their slain comrades, the Legends must now save history from a foe like none they’ve encountered in the past or future. Co-captains of the time-ship Waverider Sara Lance and Ava Sharpe have dealt with monsters, time anomalies, and most recently, villains from Hell, but this season they will face something even more challenging and bizarre … space aliens!"
"After one of their own is abducted by a ruthless alien, this new mission becomes personal. It will take more than the combined powers of a dark magician, John Constantine; a semi-reformed arsonist, Mick Rory; historian who transforms into steel, Nate Heywood; and a brother-sister wind-totem-wielding duo, Zara Tarazi and Behrad Tarazi to save the world for a sixth time. They must recruit a new Legend, a woman who was abducted by aliens when she was a child and supposedly imbued with powers that will help the team defeat their intergalactic foes. Either that or she’s just crazy…"
- Caity Lotz as Captain Sara Lance/White Canary (9/15)
- Tala Ashe as Zari Tarazi/Zari Tomaz (10/15)
- Jes Macallan as Captain Ava Sharpe (10/15)
- Olivia Swann as Astra Logue (7/15)
- Adam Tsekhman as Gary Green (8/15)
- Shayan Sobhian as Behrad Tarazi (10/15)
- Lisseth Chavez as Esperanza "Spooner" Cruz (10/15)
- Amy Louise Pemberton as Gideon (9/15)
- Nick Zano as Nate Heywood/Steel (10/15)
- Dominic Purcell as Mick Rory/Heatwave (9/15)
- Thomas Nicholson as David Bowie (2/15)
- Shawn Roberts as Spartacus (1/15)
- Raffi Barsoumian as Bishop (4/15)
- Mina Sundwall as Lita (2/15)
- David Ramsey as Bass Reeves (1/15)
- Aliyah O'Brien as Kayla (3/15)
- Jen Oleksiuk as Amelia Earhart (2/15)
- Greg Kean as Burt Beeman (1/15)
- Kirsten Robek as Rhonda Beeman (1/15)
- Mitra Lohrasb as Mrs. Taraz (1/15)
- Nic Bishop as General Kilgore/Levi Stapleton (2/15)
- Tim Perez as Fidel Castro (1/15)
- Aaron Craven as John F. Kennedy (1/15)
- AnnaLynne McCord as Irma Rose (1/15)
- Louis Lay as Niko (1/15)
- Matt Lucas as Aleister Crowley (2/15)
- Ricardo Ortiz as Fernando (1/15)
- Leo Rano as Et Gato (1/15)
- Alexander García Soto as Colonel Noreiga (1/15)
- Andy Canete as Old Farmer (1/15)
- Melissa Farman as Noelle (1/15)
|No. in series||No. in season||Episode title||Written by||Directed by||Original airdate|
|83||1||"Ground Control to Sara Lance"||James Eagan & Mark Bruner||Kevin Mock||May 2, 2021|
|84||2||"Meat: The Legends"||Matthew Maala & Morgan Faust||Rachel Talalay||May 9, 2021|
|85||3||"The Ex-Factor"||Grainne Godfree & Tyron Carter||David Geddes||May 16, 2021|
|86||4||"Bay of Squids"||Phil Klemmer||Sudz Sutherland||May 23, 2021|
|87||5||"The Satanist's Apprentice"||Keto Shimizu & Ray Utarnachitt||Caity Lotz||June 6, 2021|
|88||6||"Bishop's Gambit"||James Eagan & Emily Cheever||Kevin Mock||June 13, 2021|
|89||7||"Back to the Finale: Part II"||Morgan Faust & Mark Bruner||Glen Winter||June 20, 2021|
|90||8||"Stressed Western"||Matthew Maala||David Ramsey||June 27, 2021|
|91||9||"This Is Gus"||Tyron B. Carter||Eric Dean Seaton||July 11, 2021|
|92||10||"Bad Blood"||Grainne Godfree||Alexandra La Roche||July 18, 2021|
|93||11||"The Final Frame"||James Eagan & Ray Utarnachitt||Jes Macallan||August 8, 2021|
|94||12||"Bored on Board Onboard"||Keto Shimizu & Leah Poulliot||Harry Jierjian||August 15, 2021|
|95||13||"Silence of the Sonograms"||Phil Klemmer & Morgan Faust||Nico Sachse||August 22, 2021|
|96||14||"There Will Be Brood"||Ray Utarnachitt & Marcelena Campos Mayhorn||Maisie Richardson-Sellers||August 29, 2021|
|97||15||"The Fungus Amongus"||Keto Shimizu & James Eagan||David Geddes||September 5, 2021|
Filming for the season began in October 2020 and last until April 2021.
On October 1, 2020, Adam Tsekhman was promoted to series regular.
- On June 2, 2020, it was announced that Maisie Richardson-Sellers would not be returning as a series regular.
- On June 17, 2020, Shayan Sobhian was upped to a series regular role.
- On August 6, 2020, Olivia Swann confirmed that she would be back as a series regular.
- This season marks the final appearance of Dominic Purcell as a series regular, as he announced in a now-deleted post on April 17, 2021, that he would be leaving the series. Due to Purcell's fiery wording in the post, many fans speculated that he abruptly quit the series due to "beef" with Warner Bros. However, later that day, Purcell took to Instagram to clarify that he did not quit the series per se, but rather decided not to renew his contract which ended this season. He announced he would be returning periodically in the seventh season.
- "CW Renews Batwoman, The Flash, All American, Supergirl, Legacies + More *Update Confirmed with Full Press Release*" - SpoilerTV
- "The Legends Will Battle [Spoilers in Season 6! Plus, Who Is Returning?" - TVLine]
- "Production Dates - Various Shows *Updated 28th August 2020 with over 40 Updates*" - SpoilerTV
- "Lisseth Chavez Exits ‘Chicago P.D.’, Joins ‘DC’s Legends Of Tomorrow’ As New Series Regular In Season 6" - Deadline
- "Legends of Tomorrow promotes Adam Tsekhman to series regular for season 6" - Entertainment Weekly
- "Legends Casts TVD Alum as Sadistic Genius — Is He Season 6's Big Bad?" - TVLine
- "Legends of Tomorrow: [Spoiler Not Returning for Season 6" - TVLine]
- "‘Legends Of Tomorrow’ Ups Shayan Sobhian To Series Regular For Season 6" - Deadline
- "Legends of Tomorrow: Olivia Swann Will Be Back as Series Regular in Season 6" - TVLine